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Broughton SJ, Kitamoto T, Greenspan RJ (2004) Excitatory and inhibitory switches for courtship in the brain of Drosophila melanogaster. Curr Biol 14: 538-547

Heimbeck G, Bugnon V, Gendre N, Keller A, Stocker RF (2001) A central neural circuit for experience-independent olfactory and courtship behavior in Drosophila melanogaster. Proc Natl Acad Sci U S A 98: 15336-15341

Homberg U, Montague RA, Hildebrand JG (1988) antenno-cerebral pathways in the brain of the sphinx moth Manduca sexta. Cell Tissue Res 254:255-281.

Jefferis GS, Potter CJ, Chan AM, Marin EC, Rohlfing T, Maurer CR Jr, Luo L (2007) Comprehensive maps of Drosophila higher olfactory centers: spatially segregated fruit and pheromone representation. Cell 128:1187-1203.

Kido A, Ito K (2002) Mushroom bodies are not required for courtship behavior by normal and sexually mosaic Drosophila. J Neurobiol 52: 302-311

Malun D, Waldow U, Kraus D, Boeckh J (1993) Connections between the deutocerebrum and the protocerebrum, and neuroanatomy of several classes of deutocerebral projection neurons in the brain of male Periplaneta americana. J Comp Neurol 329:143-162.

Marin EC, Jefferis GS, Komiyama T, Zhu H, Luo L (2002) Representation of the glomerular olfactory map in the Drosophila brain. Cell 109:243-255.

Nishino H, Mizunami M (1998) Giant input neurons of the mushroom body: intracellular recording and staining in the cockroach. Neurosci Lett 246: 57-60

Nishino H, Yamashita S, Yamazaki Y, Nishikawa M, Yokohari F, Mizunami M (2003) Projection neurons originating from thermo- and hygrosensory glomeruli in the antennal lobe of the cockroach. J Comp Neurol 455: 40-55

Perez-Orive J, Mazor O, Turner GC, Cassenaer S, Wilson RI, Laurent G (2002) Oscillations and sparsening of odor representations in the mushroom body. Science 297: 359-365

Strausfeld NJ, Li Y (1999) Organization of olfactory and multimodal afferent neurons supplying the calyx and pedunculus of the cockroach mushroom bodies. J Comp Neurol 409: 603-625.

Wang Y, Chiang AS, Xia S, Kitamoto T, Tully T, Zhong Y (2003) Blockade of neurotransmission in Drosophila mushroom bodies impairs odor attraction, but not repulsion. Curr Biol 13: 1900-1904

Wong AM, Wang JW, Axel R (2002) Spatial representation of the glomerular map in the Drosophila protocerebrum. Cell 109:229-241.

Yamazaki Y, Nishikawa M, Mizunami M (1998) Three classes of GABA-like immunoreactive neurons in the mushroom body of the cockroach. Brain Res 788: 80-86