S1
Adaptations for Salt and Water Balance in Vertebrates
Organizers:
Thomas Pannabecker (Univ. Arizona, USA)
Yoshio Takei (Univ. Tokyo, Japan)
Maintenance of appropriate salt and water balance is essential for normal function of all organs. Fluid and solute fluxes across renal and non-renal epithelia and endothelia are associated with many active and passive transport pathways across cell membranes and through the paracellular pathway. Regulation of these transport pathways by multiple hormones produces systems with wide flexibility and diversity. This symposium focuses on fluid and solute transport across membranes and epithelia of renal and non-renal systems in vertebrates. Various mechanisms by which transport is achieved are considered for mammals, fish, and birds at organ, cellular, and molecular levels. For water balance, the diverse impact of aquaporins is emphasized. Hormonal systems that regulate transport pathways for fluid and solutes, and thereby influence renal hemodynamics and urine flow, through direct and indirect effects are also considered.
Speakers:
1) Thomas Pannabecker (Univ Arizona, USA)
Functional architecture of the urinary concentrating mechanism in desert rodents
2) Hiroko Nishimura (Univ. Tennessee, USA)
Avian aquaporin water channels and their regulation
3) Minoru Uchiyama (Univ. Toyama, Japan)
Urea and ammonia transporters in the cane toad, Bufo marinus and the amphibious blenny, Andamia tetradactyla
4) Christopher Cutler (Georgia Southern Univ., USA)
Characterization of aquaporin 8 isoform expression in eel (Anguilla sp.) intestine
5) Susumu Hyodo (Univ. Tokyo, Japan)
Identification and mapping of urea- and ion-transporting molecules in the kidney of cartilaginous fish